Best Describes Dna Sythesis Due to B12 Deficiency

Ditulis Roger Trevino Jumat, 29 April 2022 Tulis Komentar Edit

Vitamin B12 deficiency anemia is a low red blood cell count due to a lack deficiency of vitamin B12. Also known as cobalamin is a B vitamin that has an important role in cellular metabolism especially in DNA.

Vitamin B12 And Folate Deficiencies Flashcards Quizlet

Megaloblastic anemia is most often due to hypovitaminosis specifically vitamin B12 cobalamin and folate deficiencies which are necessary for the synthesis of DNA3.

. The anemia then leads to symptoms such as fatigue and pallor that are commonly seen in patients with B12 deficiency. There are many types of anemia. Which statement best describes the practice of fortification.

Vitamin B12 deficiency can also cause neuropsychiatric findings. Thus B12 deficiency characteristically results in the formation of hypersegmented neutrophils. Vitamin B12 deficiency due to failure to produce intrinsic factor.

In addition to correcting the deficiency an important aspect of management is determining the underlying cause because. Clinical B12 deficiency with classic haematological and neurological manifestations is relatively uncommon. The impaired DNA synthesis causes problems for other rapidly proliferating cell lines such as polymorphonuclear leukocytes PMNs.

Vitamin B 12 B12. Anemia is a condition in which the body does not have enough healthy red blood cells. Low B12 serum levels were found to have a critical role in neurological diseases such as the Alzheimers dementia and autism cardiovascular disease CAD and colorectal and breast cancer.

The chemical name for vitamin B12 is. The impaired DNA synthesis causes problems for other rapidly proliferating cell lines such as polymorphonuclear leukocytes PMNs. The anemia then leads to symptoms such as fatigue and pallor that are commonly seen in patients with B12 deficiency.

Anemia caused by a deficiency in vitamin B12 or folate. Thus B12 deficiency characteristically results in the formation of hypersegmented neutrophils. It is suggested here that reduced supply of one or other of the four deoxyribonucleoside triphosphate dNTP during the S phase of the cell cycle due to vitamin B12 or folate deficiency drug treatment or other congenital or acquired abnormality in synthesis of the dNTP impairs the cells ability to elongate newly initiated DNA fragments by preventing gap-filling the polymerase.

Terms in this set 32 define megaloblastic anemia. Also known as cobalamin is a B vitamin that has an important role in cellular metabolism especially in DNA synthesis methylation and mitochondrial metabolism. Deficiencies of vitamin B12 andor folate can cause megaloblastic anemia macrocytic anemia with other features due to impaired cell division.

Red blood cells provide oxygen to body tissues. Low dietary consumption of B12 results in respectively low serum levels which induce alterations in DNA synthesis. Vitamin B 12 B12.

Thus deficiency of B12 may lead to DNA damage. Vitamin B12 deficiency anemia. DNA synthesis developing erythroblasts are unable to replicate their DNA and divide so the cells grow bigger but cant divide.

Copper deficiency and adverse drug reactions due to drug interference with DNA synthesis are other well-known causes of megaloblastic anemia. Which list contains only vitamins that play a role in RNA and DNA synthesis. What are B12 folate used for.

Vitamin B12 And Folate Deficiencies Flashcards Quizlet